PHARMOMICS: A SPECIES- AND TISSUE-SPECIFIC DRUG SIGNATURE DATABASE AND GENE-NETWORK-BASED DRUG REPOSITIONING TOOL

PharmOmics: A species- and tissue-specific drug signature database and gene-network-based drug repositioning tool

Summary: Drug development has been hampered by a high failure rate in clinical trials due to Tub Boot Seal our incomplete understanding of drug functions across organs and species.Therefore, elucidating species- and tissue-specific drug functions can provide insights into therapeutic efficacy, potential adverse effects, and interspecies differences

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Genotype-temperature interaction in the regulation of development, growth, and morphometrics in wild-type, and growth-hormone transgenic coho salmon.

BackgroundThe neuroendocrine system is an important modulator of phenotype, directing cellular genetic responses to external cues such as temperature.Behavioural and physiological processes in poikilothermic organisms (e.g.most fishes), are particularly influenced by surrounding temperatures.Methodology/principal findingsBy comparing the developmen

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Carbon Emission Reduction Potential through Sustainable Forest Management in Forest Concession of PT Salaki Summa Sejahtera, Province of West Sumatera

A management unit GROWTH (MU) of a forest concession holder implementing the sustainable forest management (SFM) principles, could be involved in reducing Emmission from Reforestation and Forest Degradation (REDD+) and carbon trading project.The fact the strategic in implementing the REDD+ and carbon trading in MU level is still lack of pilot proje

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